An eye-opening show on Oprah about the inhumane conditions of puppy mills.
Key takeaways.
Why breed puppies when there are so many animals available for adoption who are being euthanized?
Don't buy puppies from pet stores, but get them from rescue organizations.
And spay or neuter your pet.
[7/18/13] the above link doesn't work, here's another link.  Not sure if it's referring to the same show.  I think so.
And here's an article from Best Friends,
Back in 2008, Best Friends launched our puppy mill initiatives after 
identifying puppy mills as one of the primary sources of animals 
entering our nation’s shelters. 
A revealing Best Friends–led study, just published in the current 
issue of the “Journal of the American Veterinary Medical Association,” 
adds more weight to that analysis. Led by Dr. Frank McMillan, director 
of well-being studies at Best Friends, in collaboration with a highly 
regarded research team, the study compared the behavior profiles of pet 
store puppies with those acquired from hobbyist, noncommercial breeders.
 It is estimated that 99 percent of pet store puppies are sourced from 
high-volume commercial breeders, which is to say they come from puppy 
mills. 
Dogs acquired as puppies from small, noncommercial breeders were selected for comparison for the following reasons:
1. They enter their new homes at approximately the same age as pet store pups do.
2. Their history prior to purchase is known.
3. They are, for the most part, purebred dogs. 
In fact, the only difference then between the sampled groups was the 
nature of their breeding, whelping, weaning and prolonged, stressful 
transport. One is set in a commercial breeding environment with hundreds
 or even thousands of other dogs, while the other is set in a hobby 
breeder’s home environment with only a mother dog or a small group of 
household pets. 
The difference in findings between the two groups was profound, but not surprising.
Problem behaviors exhibited by pet store dogs read like answers to a 
shelter surrender questionnaire, with the strongest effects observed in 
relation to aggressive behavior. For example, sexually intact pet store 
dogs were three times as likely to have owner-directed aggression as 
were sexually intact dogs acquired from small breeders. Pet store dogs 
were nearly twice as likely to have aggression toward unfamiliar dogs. 
Additionally, pet store dogs were also 30 to 60 percent more likely 
to have stranger-directed aggression, aggression to other household 
dogs, as well as fear of dogs and nonsocial stimuli, separation anxiety,
 and touch sensitivity. Other undesirable behaviors included escaping 
from the home, sexual mounting of people and objects, and most forms of 
house soiling. 
This Best Friends’ research effort is a follow-up to a 2011 study 
conducted by Dr. Frank and the same research team that compared adult 
puppy mill survivors to a sampling of dogs without any puppy mill 
history. The results of that study were equally dramatic, but likewise 
not at all surprising. 
The adult breeding dogs from puppy mills showed significantly 
elevated levels of fears/phobias, compulsive/repetitive behaviors, and 
heightened sensitivity to being touched. “The most prominent difference 
was in the level of fear,” says Dr. Frank. “Compared to normal pet dogs,
 the chance of recovered puppy mill dogs scoring in the highest ranges 
for fear was six to eight times higher.”
The physical abuses associated with puppy mills are well documented. 
Puppy mills are just another version of factory farming, where the 
profit margin for the mostly rural mill operators is small. Production 
cost savings are paid for on the backs of the dogs held captive for 
breeding and their pet store–bound puppies. 
For example, small cages mean that more animals can be crammed into 
limited space. Understaffed workers provide only subsistence level care 
for the dogs and pups. Low-cost, low-quality food results in dietary 
deficiencies and chronic disease. Puppies are force-weaned at an 
earlier-than-appropriate age so that they can arrive at the pet store at
 eight weeks of age. Veterinary care is nominal and is limited to the 
replacement cost of the animal. A puppy miller typically sells a pup to a
 middle man for as little as a couple of hundred dollars so the 
incentive to invest in medical care is essentially zero. Every corner 
that is cut represents a corresponding slice cut from the quality of 
life of the puppy mill dog. 
This newly published research fills in the picture of the invisible 
psychological damage that puppy mills inflict on innocent, young dogs.
The entire pet trade industry — from breeder to pet store — is a 
disgrace and needs a major overhaul. Needless to say, there is often a 
considerable desire to “save” pet store puppies by buying them, but that
 sentiment is misguided because it merely makes room for another victim.
 The best way to fight puppy mills is to never buy from a pet store or 
an online retailer. 
Many thanks to Dr. Frank and his research colleagues, James A. 
Serpell, PhD and Deborah L. Duffy, PhD from the University of 
Pennsylvania School of Veterinary Medicine, along with Elmabrok Masaoud,
 PhD and Ian R. Dohoo, DVM, PhD from the Department of Health 
Management, Atlantic Veterinary College, University of Prince Edward 
Island, Canada. Your work has given us another compelling argument in 
our campaign against the shame of puppy mills.
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